Intra-Ramanome Correlation Analysis (IRCA) algorithm was introduced to construct a metabolite conversion network from a single instance of just one sample of isogenic cells.

The Addressable Dynamic Droplet Array (aDDA) was invented for paralleled single-cell sample preparation and sequencing in a single, streamlined workflow, using yeast cells as an example. In aDDA, all the sample preparation steps, including single-cell isolation, cell lysis, amplification and product retrieval, are performed in sequence within one very small droplet.

Culture-free identification and metabolic profiling of a large collection of microalgal species based on machine learning of ramanomes.

FlowRACS, one of the first flow-mode Raman-activated cell sorter (RACS), was introduced to support high-throughput discovery and screening of enzymes and cell factories, without the need to label the cell or protein with fluorescence probes.

Using Raman microspectroscopy to predict the growth phase and metabolic state of yogurt-fermenting Lactobacillus cells during batch culture at single-cell resolution.

The RADS technology was introduced to support the functional screening of cell factories in ultra-high throughput, using the sorting of astaxanthin-hyperproducing Haematococcus pluvialis cells as an example. Vitality of the RADS-sorted cells are fully preserved, thus RADS can be directly coupled to downstream cell-culture.

An example for precise and high-throughput profiling of single-cell metabolic phenome for plant cell factories: simultaneous quantification of starch content, triglyceride content, protein content, and degree of lipid unsaturation at single-cell resolution.

Precise, rapid and low-cost sorting for Saccharomyces cerevisiae and Chlamydomonas reinhardtii at single-cell resolution.

The RAMS technology was introduced to support flow-mode Raman-activated cell sorting, using pigment-producing and non-pigment-producing yeast cells as examples.

A simple and low-cost single-cell droplet generation platform was introduced for Saccharomyces cerevisiae.