The D2O-CANST-R technology reveals, based on metabolic response and at the single-cell/organelle level, how pharmaceuticals kill cancer cells and how cancer cells adapt, while provides a novel approach for phenotype-based drug resistance tests of cancer cells.

The RAGE-Seq technology enables pathogen identification, metabolism-inhibition based antimicrobial susceptibility test and high-coverage genome sequence simultaneously at precisely one-cell resolution from a clinical urine sample.

The concept of MIC-MA and the instrument of CAST-R were introduced as a universally applicable approach for rapid antimicrobial susceptibility test and quantitative assessment of drug efficacy, based on metabolic activity inhibition at single-cell resolution.

Raman Barcode of Cellular-response to Stress (RBCS) was proposed to profile and distinguish the mechanisms of drug-response via Ramanome, which is useful for antibiotics evaluation, screening of drug-resistant bacteria and cell-drug interaction studies.