FlowRACS Chip 高通量拉曼流式分选芯片

2025.07.17 Xiaotong Ji, Xixian Wang, et al., 　　Biotechnol Biofuels Bioprod 　

Label-free isolation of lipid-rich Saccharomyces cerevisiae mutant by high-throughput flow-mode Raman-activated cell sorting and multi-omics analysis for uncovering the mechanism of enhanced lipid accumulation AREA OF INTEREST Industrial Biotech

SPECIES

Yeast

FlowRACS, Chips, Kits DOI : 10.1186/s13068-025-02677-8 PubMed : 40676605

2025.05.30 Xixian Wang, Sen Wang, Zhidian Diao, Xibao Hou, et al., 　　Proc Natl Acad Sci U S A 　

Label-free high-throughput live-cell sorting of genome-wide random mutagenesis libraries for metabolic traits by Raman flow cytometry AREA OF INTEREST Industrial Biotech

SPECIES

Fungi

FlowRACS, Chips, Kits DOI : 10.1073/pnas.2503641122 PubMed : 40445753

2025.05.19 Jia Zhang, Jianmei Wang, Pengfei Zhu, Zhidian Diao, et al., 　　iMetaOmics 　

Raman flow cytometry based single-cell species classification, viable-cell counting and vitality test for probiotic products AREA OF INTEREST Industrial Biotech

SPECIES

Bacteria

FlowRACS, Chips, Kits DOI : 10.1002/imo2.70024 PubMed :

2025.04.25 Xiaoshan Zheng, Rui Li, Ting Wang, et al., 　　Anal Chem 　

Unraveling antibacterial mechanisms of surfactants against Staphylococcus aureus via single-cell Raman spectroscopy AREA OF INTEREST Industrial Biotech

SPECIES

Bacteria

RACS-Seq, Chips, Kits DOI : 10.1021/acs.analchem.4c06380 PubMed : 40277167

2025.04.23 Xinxin Kang, Weixing Liu, et al., 　　ACS Synth Biol 　

Iron-derepressed robust production of fusarinine C siderophore by Aureobasidium melanogenum AREA OF INTEREST Industrial Biotech

SPECIES

Fungi

FlowRACS, Chips, Kits DOI : 10.1021/acssynbio.4c00897 PubMed : 40266998

2025.03.13 Huahui Chen, et al., 　　mLife 　

Engineering archaeal membrane-spanning lipid GDGT biosynthesis in bacteria: Implications for early life membrane transformations AREA OF INTEREST Environment and Agriculture

SPECIES

Bacteria

EasySort, Chips, Kits DOI : 10.1002/mlf2.70001 PubMed : 40313982

2024.11.11 Zhidian Diao, Xiaoyan Jing, Xibao Hou, et al., 　　Anal Chem 　

Artificial intelligence-assisted automatic Raman-activated cell sorting (AI-RACS) system for mining specific functional microorganisms in the microbiome AREA OF INTEREST Environment and Agriculture

SPECIES

Bacteria

Microbiome

RACS-Seq, Chips, Kits DOI : 10.1021/acs.analchem.4c03213 PubMed : 39526454

2024.09.16 Lu Sun, Min Liu, et al., 　　Helicobacter 　

Rapid antimicrobial susceptibility test of Helicobacter pylori to metronidazole via single-cell Raman spectrometry AREA OF INTEREST Medicine

SPECIES

Bacteria

RACS-Seq, Chips DOI : 10.1111/hel.13136 PubMed : 39282932

2024.09.11 Xi Sun, Xin Zhou, et al., 　　Synth Syst Biotechnol 　

Assessing the physiological properties of baker's yeast based on single-cell Raman spectrum technology AREA OF INTEREST Industrial Biotech

SPECIES

Yeast

FlowRACS, Chips DOI : 10.1016/j.synbio.2024.09.004 PubMed : 39493334

2023.08.25 Zhidian Diao, Xixian Wang, et al., 　　Biosens Bioelectron 　

Optical-based microbubble for on-demand droplet release from static droplet array (SDA) for dispensing one droplet into one tube AREA OF INTEREST Industrial Biotech

SPECIES

Bacteria

Yeast

EasySort, Chips DOI : 10.1016/j.bios.2023.115639 PubMed : 37660461

2022.12.18 Zhidian Diao, Lingyan Kan, Yilong Zhao, et al., 　　mLife 　

Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-Tube AREA OF INTEREST Industrial Biotech

SPECIES

Bacteria

Yeast

EasySort, Chips DOI : 10.1002/mlf2.12047 PubMed : 38818483

2022.11.29 Teng Xu, Yuandong Li, et al., 　　Lab Chip 　

Versatile, facile and low-cost single-cell isolation, culture and sequencing by optical tweezer-assisted pool-screening AREA OF INTEREST Industrial Biotech

SPECIES

Bacteria

Human

Yeast

EasySort, Chips DOI : 10.1039/d2lc00888b PubMed : 36477690

2022.04.18 Pengfei Zhu, Lihui Ren, Ying Zhu, Jing Dai, et al., 　　mLife 　

Rapid, automated, and reliable antimicrobial susceptibility test from positive blood culture by CAST-R AREA OF INTEREST Medicine

SPECIES

Bacteria

CAST-R, Chips, Kits DOI : 10.1002/mlf2.12019 PubMed : 38818218

2022.01.17 Yuhan Liu, Yuying Ma, Lijuan Zhang, et al., 　　J Raman Spectrosc 　

Single-cell Raman microspectroscopy-based assessment of three intracanal disinfectants’ effect on Enterococcus faecalis AREA OF INTEREST Medicine

SPECIES

Bacteria

CAST-R, Chips, Kits DOI : doi.org/10.1002/jrs.6311 PubMed :

2021.08.31 Yuehui He, et al., 　　mBio 　

Intra-Ramanome Correlation Analysis unveils metabolite conversion network from an isogenic population of cells AREA OF INTEREST Industrial Biotech

SPECIES

Algae

RACS-Seq, Chips DOI : 10.1128/mBio.01470-21 PubMed : 34465024

2021.06.29 Xiaoyan Jing，et al., 　　mSystems 　

One-Cell Metabolic Phenotyping and Sequencing of Soil Microbiome by Raman-Activated Gravity-Driven Encapsulation (RAGE) AREA OF INTEREST Environment and Agriculture

SPECIES

Bacteria

Microbiome

RACS-Seq, EasySort, Chips, Kits DOI : 10.1128/mSystems.00181-21 PubMed : 34042466

2021.06.18 Mohammadhadi Heidari Baladehi，et al., 　　Anal Chem 　

Culture-Free Identification and Metabolic Profiling of Microalgal Single Cells via Ensemble Learning of Ramanomes AREA OF INTEREST Environment and Agriculture

SPECIES

Algae

Microbiome

RACS-Seq, Chips DOI : 10.1021/acs.analchem.1c01015 PubMed : 34142549

2021.03.12 Haowei Ni, et al., 　　ISME J 　

Microbial metabolism and necromass mediated fertilization effect on soil organic carbon after long-term community incubation in different climates AREA OF INTEREST Environment and Agriculture

SPECIES

Bacteria

Microbiome

EasySort, Chips, Kits DOI : 10.1038/s41396-021-00950-w PubMed : 33712697

2021.01.12 Maryam Hekmatara, et al., 　　Anal Chem 　

D2O-probed Raman microspectroscopy distinguishes metabolic dynamics of macromolecules in organellar anticancer drug response AREA OF INTEREST Medicine

SPECIES

Human

Yeast

RACS-Seq, CAST-R, Chips, Kits DOI : 10.1021/acs.analchem.0c03925 PubMed : 33435684

2020.06.09 Teng Xu, et al., 　　Small 　

Phenome-genome profiling of single bacterial cell by Raman-Activated Gravity-Driven Encapsulation and Sequencing AREA OF INTEREST Medicine

SPECIES

Bacteria

Microbiome

RACS-Seq, EasySort, CAST-R, Chips, Kits DOI : 10.1002/smll.202001172 PubMed : 32519499

2017.11.17 Yuehui He, et al., 　　Biotechnol Biofuels 　

Label-free, simultaneous quantification of starch, protein and triacylglycerol in single microalgal cells AREA OF INTEREST Industrial Biotech

SPECIES

Algae

RACS-Seq, Chips, Kits DOI : 10.1186/s13068-017-0967-x PubMed : 29177009

2017.11.03 Xixian Wang，et al., 　　Anal Chem 　

Raman-Activated Droplet Sorting (RADS) for Label-Free High-Throughput Screening of Microalgal Single-Cells AREA OF INTEREST Industrial Biotech

SPECIES

Algae

FlowRACS, Chips, Kits DOI : 10.1021/acs.analchem.7b03884 PubMed : 29099582

2014.12.01 Yuetong Ji，et al., 　　Biotechnol J 　

Raman spectroscopy provides a rapid, non-invasive method for quantitation of starch in live, unicellular microalgae AREA OF INTEREST Industrial Biotech

SPECIES

Algae

RACS-Seq, Chips, Kits DOI : 10.1002/biot.201400165 PubMed : 24906189

2014.04.09 Tingting Wang，et al., 　　Biotechnol Biofuels 　

Quantitative dynamics of triacylglycerol accumulation in microalgae populations at single-cell resolution revealed by Raman microspectroscopy AREA OF INTEREST Industrial Biotech

SPECIES

Algae

RACS-Seq, Chips, Kits DOI : 10.1186/1754-6834-7-58 PubMed : 24716544